Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

PROBLEM: Tumor recurrence is a major clinical issue that represents the principal cause of cancer-related deaths, with few targetable common pathways. Mechanisms by which residual tumors persist and progress under a continuous shift between hypoxia-reoxygenation after neoadjuvent-therapy are unknown...

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Detalles Bibliográficos
Autores principales: Luis, Géraldine, Godfroid, Adrien, Nishiumi, Shin, Cimino, Jonathan, Blacher, Silvia, Maquoi, Erik, Wery, Coline, Collignon, Alice, Longuespée, Rémi, Montero-Ruiz, Laetitia, Dassoul, Isabelle, Maloujahmoum, Naima, Pottier, Charles, Mazzucchelli, Gabriel, Depauw, Edwin, Bellahcène, Akeila, Yoshida, Masaru, Noel, Agnès, Sounni, Nor Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163990/
https://www.ncbi.nlm.nih.gov/pubmed/34030117
http://dx.doi.org/10.1016/j.redox.2021.102006

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