Cargando…

Exogenous Plant gma-miR-159a, Identified by miRNA Library Functional Screening, Ameliorated Hepatic Stellate Cell Activation and Inflammation via Inhibiting GSK-3β-Mediated Pathways

PURPOSE: Plant-derived exogenous microRNAs (miRNAs) regulate human physiological functions by blocking the translation of target mRNAs. Although several computational approaches have been developed to elucidate the interactions of cross-species miRNAs and their targets in mammals, the number of veri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Wen-Ying, Cai, Wei, Ying, Hua-Zhong, Zhang, Wen-You, Zhang, Huan-Huan, Yu, Chen-Huan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8163999/ https://www.ncbi.nlm.nih.gov/pubmed/34079325 http://dx.doi.org/10.2147/JIR.S304828

Ejemplares similares

Nested miRNA Secondary Structure Is a Unique Determinant of miR159 Efficacy in Arabidopsis
por: Imran, Muhammad, et al.
Publicado: (2022)

Tissue-Specific Regulation of Gma-miR396 Family on Coordinating Development and Low Water Availability Responses
por: Liu, Weican, et al.
Publicado: (2017)

Biology and Function of miR159 in Plants
por: Millar, Anthony A., et al.
Publicado: (2019)

Identification of miRNAs associated with the mechanical response of hepatic stellate cells by miRNA microarray analysis
por: Yi, Suhong, et al.
Publicado: (2018)

The Expression Patterns of Exogenous Plant miRNAs in Chickens
por: Li, Hao, et al.
Publicado: (2023)

Fluctuation of Global Gene Expression by Endogenous miRNA Response to the Introduction of an Exogenous miRNA
por: Nagata, Yoshiro, et al.
Publicado: (2013)

miR-29a Modulates GSK3β/SIRT1-Linked Mitochondrial Proteostatic Stress to Ameliorate Mouse Non-Alcoholic Steatohepatitis
por: Yang, Ya-Ling, et al.
Publicado: (2020)

Exogenous loading of miRNAs into small extracellular vesicles
por: de Abreu, Ricardo C., et al.
Publicado: (2021)

Cisplatin chemotherapy-induced miRNA-210 signaling inhibits hepatocellular carcinoma cell growth
por: Yu, Huan, et al.
Publicado: (2019)

MYC and hsa-miRNA-423-5p as biomarkers in nasopharyngeal carcinoma revealed by miRNA-mRNA-pathway network integrated analysis
por: Tian, Huan, et al.
Publicado: (2017)

Sly‐miR159 regulates fruit morphology by modulating GA biosynthesis in tomato
por: Zhao, Panpan, et al.
Publicado: (2021)

Expression of miR159 Is Altered in Tomato Plants Undergoing Drought Stress
por: López-Galiano, María José, et al.
Publicado: (2019)

Downregulation of miRNA miR-1305 and upregulation of miRNA miR-6785-5p may be associated with psoriasis
por: Yan, Jianjun, et al.
Publicado: (2022)

Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR-29b-3p
por: Huan, Sheng, et al.
Publicado: (2023)

The miR167-OsARF12 module regulates rice grain filling and grain size downstream of miR159
por: Zhao, Yafan, et al.
Publicado: (2023)

The role of Exosomal miRNAs in cancer
por: Li, Chuanyun, et al.
Publicado: (2022)

Integrated Analysis of Mutations, miRNA and mRNA Expression in Glioblastoma
por: Wang, ShiChao, et al.
Publicado: (2021)

Correlation between miRNA-124, miRNA-544a, and TNF-α levels in acute spinal cord injury
por: Ma, Xiaomin, et al.
Publicado: (2022)

Gma-miR408 Enhances Soybean Cyst Nematode Susceptibility by Suppressing Reactive Oxygen Species Accumulation
por: Feng, Yaxing, et al.
Publicado: (2022)

Fine-Tuning Roles of Osa-miR159a in Rice Immunity Against Magnaporthe oryzae and Development
por: Chen, Jin-Feng, et al.
Publicado: (2021)

Downregulation of miR-486-5p in papillary thyroid carcinoma tissue: A study based on microarray and miRNA sequencing
por: Wen, Dong-Yue, et al.
Publicado: (2018)

Exogenous miRNAs induce post-transcriptional gene silencing in plants
por: Betti, Federico, et al.
Publicado: (2021)

Recent advances of NEAT1-miRNA interactions in cancer: The interactions of NEAT1 with miRNAs
por: Zhou, Hui, et al.
Publicado: (2022)

Exogenous Methyl Jasmonate Mediated MiRNA-mRNA Network Improves Heat Tolerance of Perennial Ryegrass
por: Liao, Zongchao, et al.
Publicado: (2023)

The lre‐miR159a‐LrGAMYB pathway mediates resistance to grey mould infection in Lilium regale
por: Gao, Xue, et al.
Publicado: (2020)

Ginsenoside Rh2 Ameliorates Neuropathic Pain by inhibition of the miRNA21-TLR8-mitogen-activated protein kinase axis
por: Fu, Yuan-Yuan, et al.
Publicado: (2022)

Adipogenic miRNA and meta-signature miRNAs involved in human adipocyte differentiation and obesity
por: Shi, Chunmei, et al.
Publicado: (2016)

miRNAs in vascular integrity
por: Cao, Yong, et al.
Publicado: (2017)

The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis
por: Lambrecht, Joeri, et al.
Publicado: (2015)

Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis
por: Zhao, Wei, et al.
Publicado: (2023)

Design and Application of Mini‐libraries of miRNA Probes for an Efficient and Versatile miRNA‐mRNA Cross‐linking
por: Malinowska, Anna L., et al.
Publicado: (2021)

MiRNA–miRNA synergistic network: construction via co-regulating functional modules and disease miRNA topological features
por: Xu, Juan, et al.
Publicado: (2011)

Global transcriptional and miRNA insights into bases of heterosis in hybridization of Cyprinidae
por: Zhou, Yi, et al.
Publicado: (2015)

Comprehensive analysis of miRNA profiles reveals the role of Schistosoma japonicum miRNAs at different developmental stages
por: Yu, Jie, et al.
Publicado: (2019)

The dysregulation of miRNAs in epilepsy and their regulatory role in inflammation and apoptosis
por: Xie, Guoping, et al.
Publicado: (2023)

Clearance of maternal barriers by paternal miR159 to initiate endosperm nuclear division in Arabidopsis
por: Zhao, Youshang, et al.
Publicado: (2018)

GMA 800 plus
por: Hahn, Eckhart G.
Publicado: (2011)

Integrative Analysis of miRNA-mRNA and miRNA-miRNA Interactions
por: Guo, Li, et al.
Publicado: (2014)

Genome-Wide Characterization of Salt-Responsive miRNAs, circRNAs and Associated ceRNA Networks in Tomatoes
por: Wang, Zhongyu, et al.
Publicado: (2021)

Identification of the lncRNA-miRNA-mRNA network associated with gastric cancer via integrated bioinformatics analysis
por: Ma, Xiao-Yu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_07g32l9869v7i81l48536anf7d