Protocol for detecting introgressed archaic variants with SPrime

The SPrime program detects the variants in current-day populations that were introgressed from an archaic source in the past. It is optimized for detecting introgression from Neanderthals and Denisovans in modern humans. We provide a protocol for detecting Neanderthal and Denisovan introgression in...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Browning, Sharon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164089/
https://www.ncbi.nlm.nih.gov/pubmed/34095864
http://dx.doi.org/10.1016/j.xpro.2021.100550
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author Zhou, Ying
Browning, Sharon R.
author_facet Zhou, Ying
Browning, Sharon R.
author_sort Zhou, Ying
collection PubMed
description The SPrime program detects the variants in current-day populations that were introgressed from an archaic source in the past. It is optimized for detecting introgression from Neanderthals and Denisovans in modern humans. We provide a protocol for detecting Neanderthal and Denisovan introgression in 1000 Genomes Project data, specifically focusing on the CHB (Han Chinese in Beijing) population. For complete details on the use and execution of this protocol, please refer to Browning et al. (2018).
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spelling pubmed-81640892021-06-04 Protocol for detecting introgressed archaic variants with SPrime Zhou, Ying Browning, Sharon R. STAR Protoc Protocol The SPrime program detects the variants in current-day populations that were introgressed from an archaic source in the past. It is optimized for detecting introgression from Neanderthals and Denisovans in modern humans. We provide a protocol for detecting Neanderthal and Denisovan introgression in 1000 Genomes Project data, specifically focusing on the CHB (Han Chinese in Beijing) population. For complete details on the use and execution of this protocol, please refer to Browning et al. (2018). Elsevier 2021-05-19 /pmc/articles/PMC8164089/ /pubmed/34095864 http://dx.doi.org/10.1016/j.xpro.2021.100550 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Protocol
Zhou, Ying
Browning, Sharon R.
Protocol for detecting introgressed archaic variants with SPrime
title Protocol for detecting introgressed archaic variants with SPrime
title_full Protocol for detecting introgressed archaic variants with SPrime
title_fullStr Protocol for detecting introgressed archaic variants with SPrime
title_full_unstemmed Protocol for detecting introgressed archaic variants with SPrime
title_short Protocol for detecting introgressed archaic variants with SPrime
title_sort protocol for detecting introgressed archaic variants with sprime
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164089/
https://www.ncbi.nlm.nih.gov/pubmed/34095864
http://dx.doi.org/10.1016/j.xpro.2021.100550
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