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Measuring the effect of drug treatments on primary human CD8+ T cell activation and cytolytic potential

CD8+ T cells are key effector cells in adaptive immune responses against intracellular pathogens and cancer cells. Systemic drug treatments, like chemotherapy, may positively or negatively affect CD8+ T cell function. In this protocol, we describe robust and optimized ex vivo polyclonal activation a...

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Detalles Bibliográficos
Autores principales:	Loo Yau, Helen, De Carvalho, Daniel D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164095/ https://www.ncbi.nlm.nih.gov/pubmed/34095863 http://dx.doi.org/10.1016/j.xpro.2021.100549

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