Cargando…

PRL-1 overexpressed placenta-derived mesenchymal stem cells suppress adipogenesis in Graves’ ophthalmopathy through SREBP2/HMGCR pathway

BACKGROUND: Graves’ ophthalmopathy (GO) is a disorder, in which orbital connective tissues get in inflammation and increase in volume. Stimulants such as thyroid-stimulating hormone (TSH), insulin-like growth factor 1(IGF-1), IL-1, interferon γ, and platelet-derived growth factor cause differentiati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Park, Mira, Kim, Jae Yeon, Kang, Jun Mo, Lee, Hey Jin, Banga, Jasvinder Paul, Kim, Gi Jin, Lew, Helen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164285/ https://www.ncbi.nlm.nih.gov/pubmed/34051850 http://dx.doi.org/10.1186/s13287-021-02337-2

Ejemplares similares

Human placenta-derived mesenchymal stem cells ameliorate orbital adipogenesis in female mice models of Graves’ ophthalmopathy
por: Park, Mira, et al.
Publicado: (2019)

Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy
por: Kim, Jae Yeon, et al.
Publicado: (2020)

TGFβ-Treated Placenta-Derived Mesenchymal Stem Cells Selectively Promote Anti-Adipogenesis in Thyroid-Associated Ophthalmopathy
por: Shin, Hyun-Ah, et al.
Publicado: (2022)

Chitosan inhibits inflammation and adipogenesis of orbital fibroblasts in Graves ophthalmopathy
por: Xiong, Haibo, et al.
Publicado: (2018)

Autophagy in graves’ ophthalmopathy
por: Chen, Yu-Qing, et al.
Publicado: (2023)

Inhibitory Effects of α-Lipoic Acid on Oxidative Stress-Induced Adipogenesis in Orbital Fibroblasts From Patients With Graves Ophthalmopathy
por: Hwang, Sena, et al.
Publicado: (2016)

Immunological Aspects of Graves' Ophthalmopathy
por: Łacheta, Dominika, et al.
Publicado: (2019)

AICAR-Induced Activation of AMPK Inhibits TSH/SREBP-2/HMGCR Pathway in Liver
por: Liu, Shudong, et al.
Publicado: (2015)

The Potential Role of Osteopontin in the Pathogenesis of Graves’ Ophthalmopathy
por: Lou, Heng, et al.
Publicado: (2021)

Simvastatin downregulates adipogenesis in 3T3-L1 preadipocytes and orbital fibroblasts from Graves’ ophthalmopathy patients
por: Shahida, B, et al.
Publicado: (2019)

Prostaglandin F2α Regulates Adipogenesis by Modulating Extracellular Signal-Regulated Kinase Signaling in Graves’ Ophthalmopathy
por: Zhu, Ru, et al.
Publicado: (2023)

The Influence of Juvenile Graves' Ophthalmopathy on Graves' Disease Course
por: Jankauskiene, Jurate, et al.
Publicado: (2017)

Tear-derived exosomal biomarkers of Graves’ ophthalmopathy
por: Shi, Ting-Ting, et al.
Publicado: (2022)

Enhanced orbital adipogenesis in a mouse model of T-cell-mediated autoimmunity, zymosan A-treated SKG mice: Implications for Graves’ ophthalmopathy
por: Park, Sera, et al.
Publicado: (2020)

Graves' Ophthalmopathy: A Review of Immunogenetics
por: Khalilzadeh, Omid, et al.
Publicado: (2011)

Update on the medical treatment of Graves’ ophthalmopathy
por: Griepentrog, Gregory J, et al.
Publicado: (2009)

Radiotherapy in the treatment of Graves ophthalmopathy—to do it or not?
por: Zygulska, Aneta
Publicado: (2009)

Graves’ Ophthalmopathy Misdiagnosed as Relapsing Conjunctivitis
por: Chatziralli, Irini P., et al.
Publicado: (2010)

Imaging Evaluation of the Orbit in Graves Ophthalmopathy
por: SAS, T.N., et al.
Publicado: (2015)

Precision Medicine in Graves’ Disease and Ophthalmopathy
por: Elia, Giusy, et al.
Publicado: (2021)

Graves’ Ophthalmopathy in the Setting of Primary Hypothyroidism
por: Alajmi, Sarah, et al.
Publicado: (2022)

Orbital endoscopic decompression in Graves Ophthalmopathy
por: Lima, Wilma Terezinha Anselmo, et al.
Publicado: (2015)

Activation of the EGFR-PI3K-CaM pathway by PRL-1-overexpressing placenta-derived mesenchymal stem cells ameliorates liver cirrhosis via ER stress-dependent calcium
por: Kim, Se Ho, et al.
Publicado: (2021)

Phosphatase of Regenerating Liver-1 (PRL-1)-Overexpressing Placenta-Derived Mesenchymal Stem Cells Enhance Antioxidant Effects via Peroxiredoxin 3 in TAA-Injured Rat Livers
por: Park, Hee Jung, et al.
Publicado: (2022)

Assessment of Quality of Life and Depression in Korean Patients with Graves' Ophthalmopathy
por: Lee, Hun, et al.
Publicado: (2010)

Predictive Factors of Development of Graves' Ophthalmopathy for Patients with Juvenile Graves' Disease
por: Jarusaitiene, Dalia, et al.
Publicado: (2016)

Comparative Evaluation of Oculometric Variables in Graves’ Ophthalmopathy
por: Miot, Hélio Amante, et al.
Publicado: (2009)

Severe Grave's Ophthalmopathy–missed for many years
por: Wani, Mohd Maqbool, et al.
Publicado: (2010)

Thyroid antibody-negative euthyroid Graves’ ophthalmopathy
por: Tabasum, Arshiya, et al.
Publicado: (2016)

The association of carotid cavernous fistula with Graves’ ophthalmopathy
por: Celik, Ozlem, et al.
Publicado: (2013)

The Influence of Prior Hyperthyroidism on Euthyroid Graves' Ophthalmopathy
por: Termote, Karolien, et al.
Publicado: (2014)

Cytokines as Targets of Novel Therapies for Graves’ Ophthalmopathy
por: Fallahi, Poupak, et al.
Publicado: (2021)

Current insights of applying MRI in Graves’ ophthalmopathy
por: Song, Cheng, et al.
Publicado: (2022)

Common Immunosuppressive Monotherapy for Graves’ Ophthalmopathy: A Meta-Analysis
por: Mou, Pei, et al.
Publicado: (2015)

SREBP2 is upregulated in esophageal squamous cell carcinoma and co-operates with c-Myc to regulate HMGCR expression
por: Zhong, Chenxi, et al.
Publicado: (2019)

Hypolipidemic properties of Chlorella pyrenoidosa organic acids via AMPK/HMGCR/SREBP‐1c pathway in vivo
por: Chen, Jie, et al.
Publicado: (2020)

Corticosteroid Pulse Therapy for Graves' Ophthalmopathy Reduces the Relapse Rate of Graves' Hyperthyroidism
por: Le Moli, Rosario, et al.
Publicado: (2020)

Association of variant on the promoter of cluster of differentiation 74 in graves disease and graves ophthalmopathy
por: Liu, Yu-Huei, et al.
Publicado: (2020)

Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Regulates AMPK, SREBP-2, HMGCR, and INSIG-1 Signaling and Cholesterol Metabolism In Vitro and In Vivo
por: Lee, Ki Hoon, et al.
Publicado: (2020)

The Evolving Role of Selenium in the Treatment of Graves' Disease and Ophthalmopathy
por: Duntas, Leonidas H.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_k3r78hah39q6h3lodmqtjab801