Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review

A wide number of neurological manifestations have been described in association with coronavirus disease 19 (COVID-19). We describe an unusual case of a young man who developed severe rhombencephalitis after COVID-19. He demonstrated clinical and radiological improvement with high dose corticosteroi...

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Autores principales: Jeanneret, Valerie, Winkel, Daniel, Risman, Aida, Shi, Hang, Gombolay, Grace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164357/
https://www.ncbi.nlm.nih.gov/pubmed/34082192
http://dx.doi.org/10.1016/j.jneuroim.2021.577623
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author Jeanneret, Valerie
Winkel, Daniel
Risman, Aida
Shi, Hang
Gombolay, Grace
author_facet Jeanneret, Valerie
Winkel, Daniel
Risman, Aida
Shi, Hang
Gombolay, Grace
author_sort Jeanneret, Valerie
collection PubMed
description A wide number of neurological manifestations have been described in association with coronavirus disease 19 (COVID-19). We describe an unusual case of a young man who developed severe rhombencephalitis after COVID-19. He demonstrated clinical and radiological improvement with high dose corticosteroids, plasma exchange and intravenous immune globulin. Our findings, along with previously reported cases that we review here, support an autoimmune para- or post-infectious mechanism and highlight a possible role for immunotherapy in patients with rhombencephalitis after COVID-19.
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spelling pubmed-81643572021-06-01 Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review Jeanneret, Valerie Winkel, Daniel Risman, Aida Shi, Hang Gombolay, Grace J Neuroimmunol Short Communication A wide number of neurological manifestations have been described in association with coronavirus disease 19 (COVID-19). We describe an unusual case of a young man who developed severe rhombencephalitis after COVID-19. He demonstrated clinical and radiological improvement with high dose corticosteroids, plasma exchange and intravenous immune globulin. Our findings, along with previously reported cases that we review here, support an autoimmune para- or post-infectious mechanism and highlight a possible role for immunotherapy in patients with rhombencephalitis after COVID-19. Elsevier B.V. 2021-08-15 2021-05-29 /pmc/articles/PMC8164357/ /pubmed/34082192 http://dx.doi.org/10.1016/j.jneuroim.2021.577623 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Short Communication
Jeanneret, Valerie
Winkel, Daniel
Risman, Aida
Shi, Hang
Gombolay, Grace
Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title_full Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title_fullStr Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title_full_unstemmed Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title_short Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review
title_sort post-infectious rhombencephalitis after coronavirus-19 infection: a case report and literature review
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164357/
https://www.ncbi.nlm.nih.gov/pubmed/34082192
http://dx.doi.org/10.1016/j.jneuroim.2021.577623
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