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Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164527/ https://www.ncbi.nlm.nih.gov/pubmed/34095299 http://dx.doi.org/10.1155/2021/5544188 |
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author | Song, Bo Wang, Yamei Zhu, Xiuzhi Zhang, Li Zhou, Hui Zhang, Hongmei Zhang, Tianliang Ji, Wansheng |
author_facet | Song, Bo Wang, Yamei Zhu, Xiuzhi Zhang, Li Zhou, Hui Zhang, Hongmei Zhang, Tianliang Ji, Wansheng |
author_sort | Song, Bo |
collection | PubMed |
description | The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC (P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases (P < 0.05). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia. |
format | Online Article Text |
id | pubmed-8164527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-81645272021-06-04 Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population Song, Bo Wang, Yamei Zhu, Xiuzhi Zhang, Li Zhou, Hui Zhang, Hongmei Zhang, Tianliang Ji, Wansheng Biomed Res Int Research Article The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC (P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases (P < 0.05). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia. Hindawi 2021-05-21 /pmc/articles/PMC8164527/ /pubmed/34095299 http://dx.doi.org/10.1155/2021/5544188 Text en Copyright © 2021 Bo Song et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Song, Bo Wang, Yamei Zhu, Xiuzhi Zhang, Li Zhou, Hui Zhang, Hongmei Zhang, Tianliang Ji, Wansheng Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title | Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title_full | Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title_fullStr | Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title_full_unstemmed | Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title_short | Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population |
title_sort | risk factors for gastric cancer-associated thrombotic diseases in a han chinese population |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164527/ https://www.ncbi.nlm.nih.gov/pubmed/34095299 http://dx.doi.org/10.1155/2021/5544188 |
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