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Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enr...

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Autores principales: Song, Bo, Wang, Yamei, Zhu, Xiuzhi, Zhang, Li, Zhou, Hui, Zhang, Hongmei, Zhang, Tianliang, Ji, Wansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164527/
https://www.ncbi.nlm.nih.gov/pubmed/34095299
http://dx.doi.org/10.1155/2021/5544188
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author Song, Bo
Wang, Yamei
Zhu, Xiuzhi
Zhang, Li
Zhou, Hui
Zhang, Hongmei
Zhang, Tianliang
Ji, Wansheng
author_facet Song, Bo
Wang, Yamei
Zhu, Xiuzhi
Zhang, Li
Zhou, Hui
Zhang, Hongmei
Zhang, Tianliang
Ji, Wansheng
author_sort Song, Bo
collection PubMed
description The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC (P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases (P < 0.05). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.
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spelling pubmed-81645272021-06-04 Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population Song, Bo Wang, Yamei Zhu, Xiuzhi Zhang, Li Zhou, Hui Zhang, Hongmei Zhang, Tianliang Ji, Wansheng Biomed Res Int Research Article The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC (P < 0.05), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases (P < 0.05). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia. Hindawi 2021-05-21 /pmc/articles/PMC8164527/ /pubmed/34095299 http://dx.doi.org/10.1155/2021/5544188 Text en Copyright © 2021 Bo Song et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Song, Bo
Wang, Yamei
Zhu, Xiuzhi
Zhang, Li
Zhou, Hui
Zhang, Hongmei
Zhang, Tianliang
Ji, Wansheng
Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title_full Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title_fullStr Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title_full_unstemmed Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title_short Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population
title_sort risk factors for gastric cancer-associated thrombotic diseases in a han chinese population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164527/
https://www.ncbi.nlm.nih.gov/pubmed/34095299
http://dx.doi.org/10.1155/2021/5544188
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