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Gain of CXCR7 function with mesenchymal stem cell therapy ameliorates experimental arthritis via enhancing tissue regeneration and immunomodulation
BACKGROUND: The major barriers to mesenchymal stem cell (MSC) therapy in rheumatoid arthritis (RA) are a low extent of tissue regeneration and insufficient immunomodulation after cell transplantation. In addition, the role of C-X-C chemokine receptor type 7 (CXCR7) and its mechanism of action in MSC...
Autores principales: | Wei, Sung-Tai, Huang, Yen-Chih, Chiang, Jung-Ying, Lin, Chia-Ching, Lin, Yu-Jung, Shyu, Woei-Cherng, Chen, Hui-Chen, Hsieh, Chia-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164772/ https://www.ncbi.nlm.nih.gov/pubmed/34051857 http://dx.doi.org/10.1186/s13287-021-02402-w |
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