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miR-19a/b-3p promotes inflammation during cerebral ischemia/reperfusion injury via SIRT1/FoxO3/SPHK1 pathway
BACKGROUND: Stroke affects 3–4% of adults and kills numerous people each year. Recovering blood flow with minimal reperfusion-induced injury is crucial. However, the mechanisms underlying reperfusion-induced injury, particularly inflammation, are not well understood. Here, we investigated the functi...
Autores principales: | Zhou, Feng, Wang, Yu-Kai, Zhang, Cheng-Guo, Wu, Bing-Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164774/ https://www.ncbi.nlm.nih.gov/pubmed/34051800 http://dx.doi.org/10.1186/s12974-021-02172-5 |
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