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Bromodomain and extraterminal (BET) protein inhibition of IgG/IgE production in murine B cells is counter‐balanced by a strong Th2 bias
OBJECTIVES: Inhibitors of bromodomain and extra terminal domain (BET) proteins are a new and growing class of anti‐cancer drugs, which decrease oncogene expression by targeting superenhancers. Antibody production is another physiological process relying on superenhancers, and it remains to be clarif...
Autores principales: | Dalloul, Zeinab, Best, Marie, Chenuet, Pauline, Dalloul, Iman, Le Noir, Sandrine, Togbé, Dieudonnée, Gador, Mylène, Ryffel, Bernhard, FJ Quesniaux, Valerie, El Makhour, Yolla, Boyer, François, Aldigier, Jean‐Claude, Cook‐Moreau, Jeanne, Fazilleau, Nicolas, Cogné, Michel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8164936/ https://www.ncbi.nlm.nih.gov/pubmed/34136216 http://dx.doi.org/10.1002/cti2.1280 |
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