COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide

In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additiona...

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Autores principales: Sun, Qisi, Fathy, Ramie, McMahon, Devon E., Freeman, Esther E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165093/
https://www.ncbi.nlm.nih.gov/pubmed/34556254
http://dx.doi.org/10.1016/j.det.2021.05.016
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author Sun, Qisi
Fathy, Ramie
McMahon, Devon E.
Freeman, Esther E.
author_facet Sun, Qisi
Fathy, Ramie
McMahon, Devon E.
Freeman, Esther E.
author_sort Sun, Qisi
collection PubMed
description In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection reactions were the most common cutaneous side effects observed in clinical trials; delayed injection reactions were the most common cutaneous side effect reported outside of clinical trials. Understanding the landscape of cutaneous manifestations to COVID-19 vaccines is key to providing appropriate vaccine guidance.
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spelling pubmed-81650932021-06-01 COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide Sun, Qisi Fathy, Ramie McMahon, Devon E. Freeman, Esther E. Dermatol Clin Article In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection reactions were the most common cutaneous side effects observed in clinical trials; delayed injection reactions were the most common cutaneous side effect reported outside of clinical trials. Understanding the landscape of cutaneous manifestations to COVID-19 vaccines is key to providing appropriate vaccine guidance. Elsevier Inc. 2021-10 2021-05-31 /pmc/articles/PMC8165093/ /pubmed/34556254 http://dx.doi.org/10.1016/j.det.2021.05.016 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sun, Qisi
Fathy, Ramie
McMahon, Devon E.
Freeman, Esther E.
COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title_full COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title_fullStr COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title_full_unstemmed COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title_short COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide
title_sort covid-19 vaccines and the skin: the landscape of cutaneous vaccine reactions worldwide
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165093/
https://www.ncbi.nlm.nih.gov/pubmed/34556254
http://dx.doi.org/10.1016/j.det.2021.05.016
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