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Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series
OBJECTIVE: We report a case series of 4 patients with type 1 diabetes who used hybrid closed-loop insulin pumps (Medtronic MiniMed 670 G) during hospitalization. METHODS: Clinical data and point-of-care glucose values are presented for each patient. Glucose values are shown graphically while in manu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association of Clinical Endocrinology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165117/ https://www.ncbi.nlm.nih.gov/pubmed/34095484 http://dx.doi.org/10.1016/j.aace.2020.12.013 |
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author | Atif, Zulekha Halstrom, Amanda Peragallo-Dittko, Virginia Klek, Stanislaw P. |
author_facet | Atif, Zulekha Halstrom, Amanda Peragallo-Dittko, Virginia Klek, Stanislaw P. |
author_sort | Atif, Zulekha |
collection | PubMed |
description | OBJECTIVE: We report a case series of 4 patients with type 1 diabetes who used hybrid closed-loop insulin pumps (Medtronic MiniMed 670 G) during hospitalization. METHODS: Clinical data and point-of-care glucose values are presented for each patient. Glucose values are shown graphically while in manual mode as well as in auto mode. RESULTS: The first case was a 30-year-old man admitted for pancreatitis. Mean point-of-care blood glucose was 165.7 mg/dL while in auto mode, without hypoglycemia, compared with 221 mg/dL while in manual mode. The second case was a 28-year-old woman who was admitted for a laparoscopic cholecystectomy. Mean point-of-care blood glucose in auto mode was 131.3 mg/dL, without hypoglycemia, compared with 117.6 mg/dL while in manual mode. The third case was a 46-year-old man admitted to the intensive care unit for influenzal pneumonia. Mean point-of-care blood glucose in auto mode was 159.1 mg/dL without hypoglycemia, compared with 218.5 mg/dL while in manual mode. The fourth case was a 60-year-old man who remained in auto mode throughout his hospitalization except for a period when he removed his pump for an endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. His mean point-of-care blood glucose while in auto mode was 156.8 mg/dL without hypoglycemia. CONCLUSION: These case reports support the use of hybrid closed-loop insulin-pump therapy in the inpatient setting to maintain inpatient glycemic targets and avoid hypoglycemia when part of an institution-sanctioned strategy for safe use of insulin pumps that includes point-of-care blood glucose monitoring. |
format | Online Article Text |
id | pubmed-8165117 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Association of Clinical Endocrinology |
record_format | MEDLINE/PubMed |
spelling | pubmed-81651172021-06-05 Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series Atif, Zulekha Halstrom, Amanda Peragallo-Dittko, Virginia Klek, Stanislaw P. AACE Clin Case Rep Case Report OBJECTIVE: We report a case series of 4 patients with type 1 diabetes who used hybrid closed-loop insulin pumps (Medtronic MiniMed 670 G) during hospitalization. METHODS: Clinical data and point-of-care glucose values are presented for each patient. Glucose values are shown graphically while in manual mode as well as in auto mode. RESULTS: The first case was a 30-year-old man admitted for pancreatitis. Mean point-of-care blood glucose was 165.7 mg/dL while in auto mode, without hypoglycemia, compared with 221 mg/dL while in manual mode. The second case was a 28-year-old woman who was admitted for a laparoscopic cholecystectomy. Mean point-of-care blood glucose in auto mode was 131.3 mg/dL, without hypoglycemia, compared with 117.6 mg/dL while in manual mode. The third case was a 46-year-old man admitted to the intensive care unit for influenzal pneumonia. Mean point-of-care blood glucose in auto mode was 159.1 mg/dL without hypoglycemia, compared with 218.5 mg/dL while in manual mode. The fourth case was a 60-year-old man who remained in auto mode throughout his hospitalization except for a period when he removed his pump for an endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. His mean point-of-care blood glucose while in auto mode was 156.8 mg/dL without hypoglycemia. CONCLUSION: These case reports support the use of hybrid closed-loop insulin-pump therapy in the inpatient setting to maintain inpatient glycemic targets and avoid hypoglycemia when part of an institution-sanctioned strategy for safe use of insulin pumps that includes point-of-care blood glucose monitoring. American Association of Clinical Endocrinology 2021-01-06 /pmc/articles/PMC8165117/ /pubmed/34095484 http://dx.doi.org/10.1016/j.aace.2020.12.013 Text en © 2021 AACE. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Atif, Zulekha Halstrom, Amanda Peragallo-Dittko, Virginia Klek, Stanislaw P. Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title | Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title_full | Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title_fullStr | Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title_full_unstemmed | Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title_short | Efficacy of Hybrid Closed-Loop Insulin Delivery System in a Hospital Setting: A Case Series |
title_sort | efficacy of hybrid closed-loop insulin delivery system in a hospital setting: a case series |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165117/ https://www.ncbi.nlm.nih.gov/pubmed/34095484 http://dx.doi.org/10.1016/j.aace.2020.12.013 |
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