A core-shell structured COVID-19 mRNA vaccine with favorable biodistribution pattern and promising immunity

Although inoculation of COVID-19 vaccines has rolled out globally, there is still a critical need for safe and effective vaccines to ensure fair and equitable supply for all countries. Here, we report on the development of a highly efficacious mRNA vaccine, SW0123 that is composed of sequence-modifi...

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Detalles Bibliográficos
Autores principales: Yang, Ren, Deng, Yao, Huang, Baoying, Huang, Lei, Lin, Ang, Li, Yuhua, Wang, Wenling, Liu, Jingjing, Lu, Shuaiyao, Zhan, Zhenzhen, Wang, Yufei, A, Ruhan, Wang, Wen, Niu, Peihua, Zhao, Li, Li, Shiqiang, Ma, Xiaopin, Zhang, Luyao, Zhang, Yujian, Yao, Weiguo, Liang, Xingjie, Zhao, Jincun, Liu, Zhongmin, Peng, Xiaozhong, Li, Hangwen, Tan, Wenjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165147/
https://www.ncbi.nlm.nih.gov/pubmed/34059617
http://dx.doi.org/10.1038/s41392-021-00634-z

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