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Prednisolone Suppresses the Extracellular Release of HMGB-1 and Associated Inflammatory Pathways in Kawasaki Disease

Innate immune activity plays an essential role in the development of Kawasaki disease (KD) vasculitis. Extracellular release of high mobility group box-1 (HMGB-1), an endogenous damage-associated molecular pattern protein that can activate the innate immune system and drive host inflammatory respons...

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Detalles Bibliográficos
Autores principales: Ueno, Kentaro, Nomura, Yuichi, Morita, Yasuko, Kawano, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165186/
https://www.ncbi.nlm.nih.gov/pubmed/34079539
http://dx.doi.org/10.3389/fimmu.2021.640315