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The Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas

B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...

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Detalles Bibliográficos
Autores principales: Zhang, Mengli, Zhang, Huaichao, Fu, Minjie, Zhang, Jingwen, Zhang, Cheng, Lv, Yingying, Fan, Fengfeng, Zhang, Jinsen, Xu, Hao, Ye, Dan, Yang, Hui, Hua, Wei, Mao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165280/
https://www.ncbi.nlm.nih.gov/pubmed/34079802
http://dx.doi.org/10.3389/fcell.2021.670145