Airway smooth muscle cells from severe asthma patients with fixed airflow obstruction are responsive to steroid and bronchodilator treatment in vitro

Airway smooth muscle cells from severe asthma patients with FAO respond to β(2)-agonists and corticosteroids in vitro, and at a level similar to mild asthmatics. Intrinsic dysfunction of these signalling pathways is unlikely to contribute to FAO. https://bit.ly/3muvNsW

Detalles Bibliográficos
Autores principales: Rutting, Sandra, Xenaki, Dia, Reddy, Karosham D., Baraket, Melissa, Chapman, David G., King, Gregory G., Oliver, Brian G., Tonga, Katrina O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165371/
https://www.ncbi.nlm.nih.gov/pubmed/34084782
http://dx.doi.org/10.1183/23120541.00117-2021
Descripción
Sumario:Airway smooth muscle cells from severe asthma patients with FAO respond to β(2)-agonists and corticosteroids in vitro, and at a level similar to mild asthmatics. Intrinsic dysfunction of these signalling pathways is unlikely to contribute to FAO. https://bit.ly/3muvNsW

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