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Dexmedetomidine Mitigated NLRP3-Mediated Neuroinflammation via the Ubiquitin-Autophagy Pathway to Improve Perioperative Neurocognitive Disorder in Mice

Background: Surgery and anesthesia-induced perioperative neurocognitive disorder (PND) are closely related to NOD-like receptors (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome microglia inflammatory response. Inhibiting the occurrence of neuroinflammation is an important treatment meth...

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Detalles Bibliográficos
Autores principales:	Zhang, Lieliang, Xiao, Fan, Zhang, Jing, Wang, Xifeng, Ying, Jun, Wei, Gen, Chen, Shoulin, Huang, Xiangfei, Yu, Wen, Liu, Xing, Zheng, Qingcui, Xu, Guohai, Yu, Shuchun, Hua, Fuzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165564/ https://www.ncbi.nlm.nih.gov/pubmed/34079457 http://dx.doi.org/10.3389/fphar.2021.646265

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