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(Pro)renin receptor antagonist PRO20 attenuates nephrectomy‐induced nephropathy in rats via inhibition of intrarenal RAS and Wnt/β‐catenin signaling

INTRODUCTION: (Pro)renin receptor has emerged as a new member of the renin‐angiotensin system implicated in the pathogenesis of chronic kidney disease (CKD). Herein we report characterization of the therapeutic potential of (pro)renin receptor (PRR) antagonist PRO20 in 5/6 nephrectomy (5/6Nx) rats....

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Detalles Bibliográficos
Autores principales:	Wang, Yan, Wang, Yurong, Xue, Kai, Wang, Huaijie, Zhou, Jingjing, Gao, Feng, Li, Chengde, Yang, Tianxin, Fang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165733/ https://www.ncbi.nlm.nih.gov/pubmed/34057312 http://dx.doi.org/10.14814/phy2.14881

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