Exosomal lncRNA UCA1 modulates cervical cancer stem cell self-renewal and differentiation through microRNA-122-5p/SOX2 axis

BACKGROUND: There is growing evidence discussing the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). We performed this study to explore the impact of exosomal lncRNA urothelial cancer-associated 1 (UCA1) in CC stem cells by sponging microRNA-122-5p (miR-122-5p) and regulating SOX2 ex...

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Detalles Bibliográficos
Autores principales: Gao, Zhihui, Wang, Qianqing, Ji, Mei, Guo, Xiangcui, Li, Li, Su, Xiaoke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165805/
https://www.ncbi.nlm.nih.gov/pubmed/34053467
http://dx.doi.org/10.1186/s12967-021-02872-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165805/
https://www.ncbi.nlm.nih.gov/pubmed/34053467
http://dx.doi.org/10.1186/s12967-021-02872-9

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