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Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches
Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has long been advocated as a therapy against many tumors including GBM, but how lipid metabolism is altered to suit different microenvironmental co...
Autores principales: | Shakya, Sajina, Gromovsky, Anthony D., Hale, James S., Knudsen, Arnon M., Prager, Briana, Wallace, Lisa C., Penalva, Luiz O. F., Brown, H. Alex, Kristensen, Bjarne W., Rich, Jeremy N., Lathia, Justin D., Brown, J. Mark, Hubert, Christopher G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166002/ https://www.ncbi.nlm.nih.gov/pubmed/34059134 http://dx.doi.org/10.1186/s40478-021-01205-7 |
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