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Genomic stratification based on microenvironment immune types and PD-L1 for tailoring therapeutic strategies in bladder cancer
BACKGROUND: The tumour microenvironment (TME) not only plays a role during tumour progression and metastasis but also profoundly influences treatment efficacy. Environment-mediated drug resistance is a result of crosstalk between tumour cells and stroma. The presence of a “stromal exhaustion” respon...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166145/ https://www.ncbi.nlm.nih.gov/pubmed/34059019 http://dx.doi.org/10.1186/s12885-021-08350-1 |