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HIV envelope tail truncation confers resistance to SERINC5 restriction
SERINC5 is a potent lentiviral restriction factor that gets incorporated into nascent virions and inhibits viral fusion and infectivity. The envelope glycoprotein (Env) is a key determinant for SERINC restriction, but many aspects of this relationship remain incompletely understood, and the mechanis...
Autores principales: | Haider, Tafhima, Snetkov, Xenia, Jolly, Clare |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166163/ https://www.ncbi.nlm.nih.gov/pubmed/34001619 http://dx.doi.org/10.1073/pnas.2101450118 |
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