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Joint cell segmentation and cell type annotation for spatial transcriptomics

RNA hybridization‐based spatial transcriptomics provides unparalleled detection sensitivity. However, inaccuracies in segmentation of image volumes into cells cause misassignment of mRNAs which is a major source of errors. Here, we develop JSTA, a computational framework for joint cell segmentation...

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Detalles Bibliográficos
Autores principales:	Littman, Russell, Hemminger, Zachary, Foreman, Robert, Arneson, Douglas, Zhang, Guanglin, Gómez‐Pinilla, Fernando, Yang, Xia, Wollman, Roy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166214/ https://www.ncbi.nlm.nih.gov/pubmed/34057817 http://dx.doi.org/10.15252/msb.202010108

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