Cargando…

CXCL1 Regulated by miR-302e Is Involved in Cell Viability and Motility of Colorectal Cancer via Inhibiting JAK-STAT Signaling Pathway

PURPOSE: This study made a systemic description for the CXCL1-dependent regulatory mechanism in colorectal cancer (CRC). METHODS: Bioinformatics methods were applied to obtain target mRNA CXCL1 and corresponding upstream miRNA. qRT-PCR and Western blot were performed to measure the levels of CXCL1 a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Biyin, Song, Li, Nie, Xiuzhen, Lin, Fangfeng, Yu, Zongyang, Kong, Wencui, Qi, Xiaoyan, Wang, Wenwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166233/ https://www.ncbi.nlm.nih.gov/pubmed/34079750 http://dx.doi.org/10.3389/fonc.2020.577229

Ejemplares similares

Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathway
por: Liu, Jiafei, et al.
Publicado: (2019)

The involvement of JAK-STAT3 in cell motility, invasion, and metastasis
por: Teng, Yong, et al.
Publicado: (2014)

miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability
por: Parchem, Ronald J., et al.
Publicado: (2015)

Gene Mutation and Its Association with Clinicopathological Features in Young Patients with Non-Small-Cell Lung Cancer
por: Kong, Wencui, et al.
Publicado: (2022)

miR-155 meets the JAK/STAT pathway
por: Persson, Jenny Liao
Publicado: (2013)

An inhibitor of cholesterol absorption displays anti-myeloma activity by targeting the JAK2-STAT3 signaling pathway
por: Xu, Xin, et al.
Publicado: (2016)

miR-302c-3p and miR-520a-3p suppress the proliferation of cervical carcinoma cells by targeting CXCL8
por: Ding, Hong-Mei, et al.
Publicado: (2021)

The microRNA and the perspectives of miR-302
por: Chen, Emily Yen Yu, et al.
Publicado: (2019)

CXCL6 Promotes Renal Interstitial Fibrosis in Diabetic Nephropathy by Activating JAK/STAT3 Signaling Pathway
por: Sun, Meng-Yao, et al.
Publicado: (2019)

miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44
por: Sun, Lina, et al.
Publicado: (2019)

JAKs and STATs in chemoresistance
por: Costa-Pereira, Ana P
Publicado: (2010)

JAK-STAT and feeding
por: Ladyman, Sharon R., et al.
Publicado: (2013)

CXCL8 Promotes Glioma Progression By Activating The JAK/STAT1/HIF-1α/Snail Signaling Axis
por: Chen, Zhiming, et al.
Publicado: (2019)

Hesperetin reverses P-glycoprotein-mediated cisplatin resistance in DDP-resistant human lung cancer cells via modulation of the nuclear factor-κB signaling pathway
por: Kong, Wencui, et al.
Publicado: (2020)

Effect of JAK Inhibitors on Release of CXCL9, CXCL10 and CXCL11 from Human Airway Epithelial Cells
por: Fenwick, Peter S., et al.
Publicado: (2015)

Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells
por: Russell, Mark A., et al.
Publicado: (2013)

Hypoxia-Induced Activation of JAK/STAT3 Signaling Pathway Promotes Trophoblast Cell Viability and Angiogenesis in Preeclampsia
por: Xu, Chengfang, et al.
Publicado: (2017)

CEP55 Promotes Cell Motility via JAK2–STAT3–MMPs Cascade in Hepatocellular Carcinoma
por: Li, Minjing, et al.
Publicado: (2018)

MicroRNA-204 Inhibits the Growth and Motility of Colorectal Cancer Cells by Downregulation of CXCL8
por: Shuai, Feng, et al.
Publicado: (2018)

Delamanid suppresses CXCL10 expression via regulation of JAK/STAT1 signaling and correlates with reduced inflammation in tuberculosis patients
por: Qiao, Min, et al.
Publicado: (2022)

CXCL8 Promotes Glioma Progression by Activating the JAK/STAT1/HIF-1α/Snail Signaling Axis [Retraction]
Publicado: (2023)

A JAK/STAT invasion
por: Wells, William A.
Publicado: (2002)

JAK-STAT and bone metabolism
por: Li, Jiliang
Publicado: (2013)

The Drosophila JAK-STAT pathway
por: Zeidler, Martin P, et al.
Publicado: (2013)

Evolution of the JAK-STAT pathway
por: Liongue, Clifford, et al.
Publicado: (2013)

The JAK-STAT pathway at 20
por: Darnell, Jr., James E.
Publicado: (2012)

JAK-STAT in lymphoproliferative disorders
por: Rabadan, Raul, et al.
Publicado: (2015)

Depletion of Fibroblast Growth Factor 12 Restrains the Viability, Stemness, and Motility of Colorectal Cancer
por: Gao, Xueyuan, et al.
Publicado: (2022)

Cisplatin or Doxorubicin Reduces Cell Viability via the PTPIVA3-JAK2-STAT3 Cascade in Hepatocellular Carcinoma
por: Li, Chao-Jen, et al.
Publicado: (2023)

An overview of JAK/STAT pathways and JAK inhibition in alopecia areata
por: Lensing, Maddison, et al.
Publicado: (2022)

Mechanisms of JAK-STAT signaling pathway mediated by CXCL8 gene silencing on epithelial-mesenchymal transition of human cutaneous melanoma cells
por: Hu, Xiaorui, et al.
Publicado: (2020)

ErHuang Formula Improves Renal Fibrosis in Diabetic Nephropathy Rats by Inhibiting CXCL6/JAK/STAT3 Signaling Pathway
por: Shen, Yu-Li, et al.
Publicado: (2020)

A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway
por: Zhang, Zubin, et al.
Publicado: (2016)

The Role of ARL4C in Erlotinib Resistance: Activation of the Jak2/Stat 5/β-Catenin Signaling Pathway
por: Liao, Jinrong, et al.
Publicado: (2020)

Pazopanib as salvage therapy in metastatic renal cell carcinoma with hypercalcemic crisis and renal insufficiency: a case report and literature review
por: Chen, Ying, et al.
Publicado: (2020)

IL6R inhibits viability and apoptosis of pancreatic beta-cells in type 2 diabetes mellitus via regulation by miR-22 of the JAK/STAT signaling pathway
por: Wu, Xinhua, et al.
Publicado: (2019)

MiR-101 Protects Against the Cerebral I/R Injury Through Regulating JAK2/STAT3 Signaling Pathway
por: Guo, Xiaowang, et al.
Publicado: (2021)

Regulation of somatic cell reprogramming through inducible mir-302 expression
por: Lin, Shi-Lung, et al.
Publicado: (2011)

miR-302e Suppresses Glioma Progression by Targeting VEGFA
por: Xie, Yunpeng, et al.
Publicado: (2020)

Correction: A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway
por: Zhang, Zubin, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_k0ko05r6e23ut37cghujc3gbus