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An Integrated Computational and Experimental Approach to Identifying Inhibitors for SARS-CoV-2 3CL Protease

The newly evolved SARS-CoV-2 has caused the COVID-19 pandemic, and the SARS-CoV-2 main protease 3CLpro is essential for the rapid replication of the virus. Inhibiting this protease may open an alternative avenue toward therapeutic intervention. In this work, a computational docking approach was deve...

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Detalles Bibliográficos
Autores principales:	Zhai, Tianhua, Zhang, Fangyuan, Haider, Shozeb, Kraut, Daniel, Huang, Zuyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166273/ https://www.ncbi.nlm.nih.gov/pubmed/34079818 http://dx.doi.org/10.3389/fmolb.2021.661424

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