Cargando…

Nano-Sized Hydroxyapatite Induces Apoptosis and Osteogenic Differentiation of Vascular Smooth Muscle Cells via JNK/c-JUN Pathway

PURPOSE: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression. METHODS: Transmission electron microscop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qi, Xiang, Pingping, Chen, Mingyao, Luo, Yi, Zhao, Yun, Zhu, Jinyun, Jing, Wangwei, Yu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166281/ https://www.ncbi.nlm.nih.gov/pubmed/34079254 http://dx.doi.org/10.2147/IJN.S303714

Ejemplares similares

Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells
por: Liu, Qi, et al.
Publicado: (2021)

Osteogenic Potential of Nano-Hydroxyapatite and Strontium-Substituted Nano-Hydroxyapatite
por: Kontogianni, Georgia-Ioanna, et al.
Publicado: (2023)

The Role of Sirtuins in Osteogenic Differentiation of Vascular Smooth Muscle Cells and Vascular Calcification
por: Wang, Shuangshuang, et al.
Publicado: (2022)

Osteomodulin attenuates smooth muscle cell osteogenic transition in vascular calcification
por: Skenteris, Nikolaos T., et al.
Publicado: (2022)

Antimicrobial and Osteogenic Effects of Collagen Membrane Decorated with Chitosan–Nano-Hydroxyapatite
por: Lazarevic, Milos, et al.
Publicado: (2023)

Epoxyeicosatrienoic Acid Inhibits the Apoptosis of Cerebral Microvascular Smooth Muscle Cells by Oxygen Glucose Deprivation via Targeting the JNK/c-Jun and mTOR Signaling Pathways
por: Qu, Youyang, et al.
Publicado: (2017)

YAP/TAZ Are Required to Suppress Osteogenic Differentiation of Vascular Smooth Muscle Cells
por: Wang, Lei, et al.
Publicado: (2020)

Zinc Ameliorates the Osteogenic Effects of High Glucose in Vascular Smooth Muscle Cells
por: Henze, Laura A., et al.
Publicado: (2021)

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells
por: Alesutan, Ioana, et al.
Publicado: (2017)

Promotion of In Vitro Osteogenic Activity by Melt Extrusion-Based PLLA/PCL/PHBV Scaffolds Enriched with Nano-Hydroxyapatite and Strontium Substituted Nano-Hydroxyapatite
por: Kontogianni, Georgia-Ioanna, et al.
Publicado: (2023)

Suppression of Wnt Signaling and Osteogenic Changes in Vascular Smooth Muscle Cells by Eicosapentaenoic Acid
por: Saito, Yukihiro, et al.
Publicado: (2017)

Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification
por: Pustlauk, Wera, et al.
Publicado: (2020)

Interaction of alginate with nano-hydroxyapatite-collagen using strontium provides suitable osteogenic platform
por: Hassani, Ayla, et al.
Publicado: (2022)

MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cells
por: Han, Yingchun, et al.
Publicado: (2021)

LncRNA BANCR facilitates vascular smooth muscle cell proliferation and migration through JNK pathway
por: Li, He, et al.
Publicado: (2017)

The osteogenic differentiation of human dental pulp stem cells in alginate-gelatin/Nano-hydroxyapatite microcapsules
por: Alipour, Mahdieh, et al.
Publicado: (2021)

Osteogenic and anti-inflammatory effect of the multifunctional bionic hydrogel scaffold loaded with aspirin and nano-hydroxyapatite
por: Li, Shaoping, et al.
Publicado: (2023)

Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells
por: Montes de Oca, Addy, et al.
Publicado: (2014)

Role of SGK1 in the Osteogenic Transdifferentiation and Calcification of Vascular Smooth Muscle Cells Promoted by Hyperglycemic Conditions
por: Poetsch, Florian, et al.
Publicado: (2020)

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification
por: Seime, Till, et al.
Publicado: (2021)

Corrigendum: Osteogenic and anti-inflammatory effect of the multifunctional bionic hydrogel scaffold loaded with aspirin and nano-hydroxyapatite
por: Li, Shaoping, et al.
Publicado: (2023)

Improvement of the mechanical properties and osteogenic activity of 3D-printed polylactic acid porous scaffolds by nano-hydroxyapatite and nano-magnesium oxide
por: Xu, Dian, et al.
Publicado: (2022)

Nano Sized Hydroxyapatite-Polylactic Acid-Vancomycin in Alleviation of Chronic Osteomyelitis
por: Lv, Xiao-Feng, et al.
Publicado: (2022)

C-Jun Nh(2)-Terminal Kinase (Jnk)1 and Jnk2 Have Similar and Stage-Dependent Roles in Regulating T Cell Apoptosis and Proliferation
por: Sabapathy, Kanaga, et al.
Publicado: (2001)

p53 negatively regulates the osteogenic differentiation of vascular smooth muscle cells in mice with chronic kidney disease
por: Li, KL, et al.
Publicado: (2012)

Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT
por: Tyson, John, et al.
Publicado: (2020)

Diethyl citrate and sodium citrate reduce the cytotoxic effects of nanosized hydroxyapatite crystals on mouse vascular smooth muscle cells
por: Zhang, Chong-Yu, et al.
Publicado: (2017)

Ubiquitin-specific protease 47 is associated with vascular calcification in chronic kidney disease by regulating osteogenic transdifferentiation of vascular smooth muscle cells
por: Xiao, Qiong, et al.
Publicado: (2022)

Age decreases mitochondrial motility and increases mitochondrial size in vascular smooth muscle
por: Chalmers, Susan, et al.
Publicado: (2016)

Synergistic Effect of Micro-Nano-Hybrid Surfaces and Sr Doping on the Osteogenic and Angiogenic Capacity of Hydroxyapatite Bioceramics Scaffolds
por: Jiang, Shengjie, et al.
Publicado: (2022)

Cytokine regulation of apoptosis-induced apoptosis and apoptosis-induced cell proliferation in vascular smooth muscle cells
por: Aravani, Dimitra, et al.
Publicado: (2020)

Comparative study of hydroxyapatite, fluor-hydroxyapatite and Si-substituted hydroxyapatite nanoparticles on osteogenic, osteoclastic and antibacterial ability
por: Sun, Jing, et al.
Publicado: (2019)

Support for the initial attachment, growth and differentiation of MG-63 cells: a comparison between nano-size hydroxyapatite and micro-size hydroxyapatite in composites
por: Filová, Elena, et al.
Publicado: (2014)

Niacin Suppresses Progression of Atherosclerosis by Inhibiting Vascular Inflammation and Apoptosis of Vascular Smooth Muscle Cells
por: Su, Gang, et al.
Publicado: (2015)

Alarmins and c-Jun N-Terminal Kinase (JNK) Signaling in Neuroinflammation
por: Anfinogenova, Nina D., et al.
Publicado: (2020)

The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases
por: Chen, Jing, et al.
Publicado: (2021)

Tormentic acid inhibits proliferation and induces apoptosis in vascular smooth muscle cells
por: Fogo, AS, et al.
Publicado: (2003)

Effect of Oxysterol-Induced Apoptosis of Vascular Smooth Muscle Cells on Experimental Hypercholesterolemia
por: Perales, Sonia, et al.
Publicado: (2009)

Sclerostin is involved in osteogenic transdifferentiation of vascular smooth muscle cells in chronic kidney disease-associated vascular calcification with non-canonical Wnt signaling
por: Xiao, Qiong, et al.
Publicado: (2022)

Adropin Inhibits Vascular Smooth Muscle Cell Osteogenic Differentiation to Alleviate Vascular Calcification via the JAK2/STAT3 Signaling Pathway
por: Wang, Li, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_embedtafa4mqdprgqf5dutp7l8