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Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia

AIM: Our study aims to produce an estimation of the keratoconus disease epidemiology and important demographic factors in disease presentation in Najran city in the south of Saudi Arabia. METHODS: Keratoconus patients between 9 and 29 years of age at the eye clinic of King Khaled General Hospital in...

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Autores principales: Alzahrani, Khaled, Al-Rashah, Ali, Al-Salem, Salem, Al-Murdif, Yahya, Al-Rashah, Abdalaziz, Alrashah, Alhassan, Al-Faify, Noura, Ibrahim, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166355/
https://www.ncbi.nlm.nih.gov/pubmed/34079417
http://dx.doi.org/10.2147/OPTO.S309651
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author Alzahrani, Khaled
Al-Rashah, Ali
Al-Salem, Salem
Al-Murdif, Yahya
Al-Rashah, Abdalaziz
Alrashah, Alhassan
Al-Faify, Noura
Ibrahim, Mohammed
author_facet Alzahrani, Khaled
Al-Rashah, Ali
Al-Salem, Salem
Al-Murdif, Yahya
Al-Rashah, Abdalaziz
Alrashah, Alhassan
Al-Faify, Noura
Ibrahim, Mohammed
author_sort Alzahrani, Khaled
collection PubMed
description AIM: Our study aims to produce an estimation of the keratoconus disease epidemiology and important demographic factors in disease presentation in Najran city in the south of Saudi Arabia. METHODS: Keratoconus patients between 9 and 29 years of age at the eye clinic of King Khaled General Hospital in Najran Province with a confirmed diagnosis of keratoconus were recruited over one year period. Visual acuity, keratometry, corneal thickness and demographic data were collected and analysed. RESULTS: The keratoconus prevalence in Najran Province was found to be 87.3 cases per 100,000 people with an incidence of 28.47 per 100,000 cases. The disease presented more frequently in male patients (67.9%) with a statistically significant difference in the mean age between genders (p=0.014). Most cases presented at a moderate stage, and almost half of the cases reported a family history of the disease. There were statistically significant differences in best visual acuity and corneal thickness between genders (p<0.05). The majority of the cases were managed with contact lenses (56.08%). CONCLUSION: Genetic and environmental factors could have a substantial role in the increased rate of keratoconus presentation in Najran Province. Screening programmes should dedicate more attention to late presentation to improve prevention and early detection. More studies on keratoconus epidemiology in Saudi Arabia are needed.
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spelling pubmed-81663552021-06-01 Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia Alzahrani, Khaled Al-Rashah, Ali Al-Salem, Salem Al-Murdif, Yahya Al-Rashah, Abdalaziz Alrashah, Alhassan Al-Faify, Noura Ibrahim, Mohammed Clin Optom (Auckl) Original Research AIM: Our study aims to produce an estimation of the keratoconus disease epidemiology and important demographic factors in disease presentation in Najran city in the south of Saudi Arabia. METHODS: Keratoconus patients between 9 and 29 years of age at the eye clinic of King Khaled General Hospital in Najran Province with a confirmed diagnosis of keratoconus were recruited over one year period. Visual acuity, keratometry, corneal thickness and demographic data were collected and analysed. RESULTS: The keratoconus prevalence in Najran Province was found to be 87.3 cases per 100,000 people with an incidence of 28.47 per 100,000 cases. The disease presented more frequently in male patients (67.9%) with a statistically significant difference in the mean age between genders (p=0.014). Most cases presented at a moderate stage, and almost half of the cases reported a family history of the disease. There were statistically significant differences in best visual acuity and corneal thickness between genders (p<0.05). The majority of the cases were managed with contact lenses (56.08%). CONCLUSION: Genetic and environmental factors could have a substantial role in the increased rate of keratoconus presentation in Najran Province. Screening programmes should dedicate more attention to late presentation to improve prevention and early detection. More studies on keratoconus epidemiology in Saudi Arabia are needed. Dove 2021-05-27 /pmc/articles/PMC8166355/ /pubmed/34079417 http://dx.doi.org/10.2147/OPTO.S309651 Text en © 2021 Alzahrani et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Alzahrani, Khaled
Al-Rashah, Ali
Al-Salem, Salem
Al-Murdif, Yahya
Al-Rashah, Abdalaziz
Alrashah, Alhassan
Al-Faify, Noura
Ibrahim, Mohammed
Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title_full Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title_fullStr Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title_full_unstemmed Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title_short Keratoconus Epidemiology Presentations at Najran Province, Saudi Arabia
title_sort keratoconus epidemiology presentations at najran province, saudi arabia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166355/
https://www.ncbi.nlm.nih.gov/pubmed/34079417
http://dx.doi.org/10.2147/OPTO.S309651
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