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Primary endobronchial paraganglioma with lymph node metastasis: a case report
A paraganglioma is an extra-adrenal tumor of the paraganglia often found in association with sympathetic and parasympathetic nerves. A primary pulmonary paraganglioma generally presents as multiple small tumors or a solitary mass; however, endobronchial involvement is extremely rare. A 49-year-old m...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166387/ https://www.ncbi.nlm.nih.gov/pubmed/33771069 http://dx.doi.org/10.1177/03000605211003014 |
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author | Huang, Xiao-jun Wu, Chengxiang Chen, Xi-yuan |
author_facet | Huang, Xiao-jun Wu, Chengxiang Chen, Xi-yuan |
author_sort | Huang, Xiao-jun |
collection | PubMed |
description | A paraganglioma is an extra-adrenal tumor of the paraganglia often found in association with sympathetic and parasympathetic nerves. A primary pulmonary paraganglioma generally presents as multiple small tumors or a solitary mass; however, endobronchial involvement is extremely rare. A 49-year-old man was admitted to our hospital because of a chronic cough, intermittent dyspnea, and chest pain. Chest computed tomography revealed a rounded, high-density lesion in the left lower lung lobe. Fiberoptic bronchoscopy demonstrated an endobronchial mass characterized by smooth, hypervascularized mucosa. Transbronchial biopsy of the mass and immunohistochemistry results suggested a paraganglioma. The patient fully recovered after lobectomy and lymphadenectomy. Pulmonary paragangliomas are rarely reported. Complete surgical resection is considered the treatment of choice for pulmonary paragangliomas, and the long-term prognosis is generally good. However, life-long follow-up is mandatory because of the possibility of recurrence and metastasis. This case report adds valuable knowledge to the literature on pulmonary paragangliomas. |
format | Online Article Text |
id | pubmed-8166387 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-81663872021-06-07 Primary endobronchial paraganglioma with lymph node metastasis: a case report Huang, Xiao-jun Wu, Chengxiang Chen, Xi-yuan J Int Med Res Case Reports A paraganglioma is an extra-adrenal tumor of the paraganglia often found in association with sympathetic and parasympathetic nerves. A primary pulmonary paraganglioma generally presents as multiple small tumors or a solitary mass; however, endobronchial involvement is extremely rare. A 49-year-old man was admitted to our hospital because of a chronic cough, intermittent dyspnea, and chest pain. Chest computed tomography revealed a rounded, high-density lesion in the left lower lung lobe. Fiberoptic bronchoscopy demonstrated an endobronchial mass characterized by smooth, hypervascularized mucosa. Transbronchial biopsy of the mass and immunohistochemistry results suggested a paraganglioma. The patient fully recovered after lobectomy and lymphadenectomy. Pulmonary paragangliomas are rarely reported. Complete surgical resection is considered the treatment of choice for pulmonary paragangliomas, and the long-term prognosis is generally good. However, life-long follow-up is mandatory because of the possibility of recurrence and metastasis. This case report adds valuable knowledge to the literature on pulmonary paragangliomas. SAGE Publications 2021-03-26 /pmc/articles/PMC8166387/ /pubmed/33771069 http://dx.doi.org/10.1177/03000605211003014 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Reports Huang, Xiao-jun Wu, Chengxiang Chen, Xi-yuan Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title | Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title_full | Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title_fullStr | Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title_full_unstemmed | Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title_short | Primary endobronchial paraganglioma with lymph node metastasis: a case report |
title_sort | primary endobronchial paraganglioma with lymph node metastasis: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166387/ https://www.ncbi.nlm.nih.gov/pubmed/33771069 http://dx.doi.org/10.1177/03000605211003014 |
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