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“Metalloestrogenic” effects of cadmium downstream of G protein-coupled estrogen receptor and mitogen-activated protein kinase pathways in human uterine fibroid cells

Cadmium (Cd) is a toxic metal reported to act as an estrogen “mimic” in the rat uterus and in vitro. We have reported that Cd stimulates proliferation of estrogen-responsive human uterine leiomyoma (ht-UtLM; fibroid) cells through nongenomic signaling involving the G protein-coupled estrogen recepto...

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Detalles Bibliográficos
Autores principales: Yu, Linda, Liu, Jingli, Yan, Yitang, Burwell, Alanna, Castro, Lysandra, Shi, Min, Dixon, Darlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166678/
https://www.ncbi.nlm.nih.gov/pubmed/33818655
http://dx.doi.org/10.1007/s00204-021-03033-z