A conserved residue in the P2X4 receptor has a nonconserved function in ATP recognition

Highly conserved amino acids are generally anticipated to have similar functions across a protein superfamily, including that of the P2X ion channels, which are gated by extracellular ATP. However, whether and how these functions are conserved becomes less clear when neighboring amino acids are not...

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Detalles Bibliográficos
Autores principales: Chen, Ping-Fang, Ma, Xue-Fei, Sun, Liang-Fei, Tian, Yun, Fan, Ying-Zhe, Li, Peiwang, Xiao, Zhihong, Zhu, Michael X., Guo, Chang-Run, Li, Changzhu, Yu, Ye, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166750/
https://www.ncbi.nlm.nih.gov/pubmed/33901491
http://dx.doi.org/10.1016/j.jbc.2021.100655

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