Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease

Iron homeostasis disturbance has been implicated in Alzheimer’s disease (AD), and excess iron exacerbates oxidative damage and cognitive defects. Ferroptosis is a nonapoptotic form of cell death dependent upon intracellular iron. However, the involvement of ferroptosis in the pathogenesis of AD rema...

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Detalles Bibliográficos
Autores principales: Bao, Wen-Dai, Pang, Pei, Zhou, Xiao-Ting, Hu, Fan, Xiong, Wan, Chen, Kai, Wang, Jing, Wang, Fudi, Xie, Dong, Hu, Ya-Zhuo, Han, Zhi-Tao, Zhang, Hong-Hong, Wang, Wang-Xia, Nelson, Peter T., Chen, Jian-Guo, Lu, Youming, Man, Heng-Ye, Liu, Dan, Zhu, Ling-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166828/
https://www.ncbi.nlm.nih.gov/pubmed/33398092
http://dx.doi.org/10.1038/s41418-020-00685-9

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