Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity and contributes to tissue injury, followed by severe organ damage. Pharmacological or genetic inhibition of NET release reduces pathology in multiple inflammatory disease models, indicating that NETs are p...

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Detalles Bibliográficos
Autores principales: Chirivi, Renato G. S., van Rosmalen, Jos W. G., van der Linden, Maarten, Euler, Maximilien, Schmets, Gonny, Bogatkevich, Galina, Kambas, Konstantinos, Hahn, Jonas, Braster, Quinte, Soehnlein, Oliver, Hoffmann, Markus H., Es, Helmuth H. G. van, Raats, Jos M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/
https://www.ncbi.nlm.nih.gov/pubmed/32203195
http://dx.doi.org/10.1038/s41423-020-0381-3

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