Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity and contributes to tissue injury, followed by severe organ damage. Pharmacological or genetic inhibition of NET release reduces pathology in multiple inflammatory disease models, indicating that NETs are p...

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Prif Awduron: Chirivi, Renato G. S., van Rosmalen, Jos W. G., van der Linden, Maarten, Euler, Maximilien, Schmets, Gonny, Bogatkevich, Galina, Kambas, Konstantinos, Hahn, Jonas, Braster, Quinte, Soehnlein, Oliver, Hoffmann, Markus H., Es, Helmuth H. G. van, Raats, Jos M. H.
Fformat: Online Erthygl Texto
Iaith:English
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/
https://www.ncbi.nlm.nih.gov/pubmed/32203195
http://dx.doi.org/10.1038/s41423-020-0381-3

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/
https://www.ncbi.nlm.nih.gov/pubmed/32203195
http://dx.doi.org/10.1038/s41423-020-0381-3

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