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Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases
Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity and contributes to tissue injury, followed by severe organ damage. Pharmacological or genetic inhibition of NET release reduces pathology in multiple inflammatory disease models, indicating that NETs are p...
Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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Μορφή: | Online Άρθρο Κείμενο |
Γλώσσα: | English |
Έκδοση: |
Nature Publishing Group UK
2020
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Θέματα: | |
Διαθέσιμο Online: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/ https://www.ncbi.nlm.nih.gov/pubmed/32203195 http://dx.doi.org/10.1038/s41423-020-0381-3 |