Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases

Excessive release of neutrophil extracellular traps (NETs) is associated with disease severity and contributes to tissue injury, followed by severe organ damage. Pharmacological or genetic inhibition of NET release reduces pathology in multiple inflammatory disease models, indicating that NETs are p...

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Détails bibliographiques
Auteurs principaux: Chirivi, Renato G. S., van Rosmalen, Jos W. G., van der Linden, Maarten, Euler, Maximilien, Schmets, Gonny, Bogatkevich, Galina, Kambas, Konstantinos, Hahn, Jonas, Braster, Quinte, Soehnlein, Oliver, Hoffmann, Markus H., Es, Helmuth H. G. van, Raats, Jos M. H.
Format: Online Article Texte
Langue:English
Publié: Nature Publishing Group UK 2020
Sujets:
Article
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/
https://www.ncbi.nlm.nih.gov/pubmed/32203195
http://dx.doi.org/10.1038/s41423-020-0381-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166830/
https://www.ncbi.nlm.nih.gov/pubmed/32203195
http://dx.doi.org/10.1038/s41423-020-0381-3

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