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Model-based analysis uncovers mutations altering autophagy selectivity in human cancer

Autophagy can selectively target protein aggregates, pathogens, and dysfunctional organelles for the lysosomal degradation. Aberrant regulation of autophagy promotes tumorigenesis, while it is far less clear whether and how tumor-specific alterations result in autophagic aberrance. To form a link be...

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Detalles Bibliográficos
Autores principales:	Han, Zhu, Zhang, Weizhi, Ning, Wanshan, Wang, Chenwei, Deng, Wankun, Li, Zhidan, Shang, Zehua, Shen, Xiaofei, Liu, Xiaohui, Baba, Otto, Morita, Tsuyoshi, Chen, Lu, Xue, Yu, Jia, Da
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166871/ https://www.ncbi.nlm.nih.gov/pubmed/34059679 http://dx.doi.org/10.1038/s41467-021-23539-5

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