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Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling

Intestinal barrier function defects and dysregulation of intestinal immune responses are two key contributory factors in the pathogenesis of ulcerative colitis (UC). Phenazine biosynthesis-like domain-containing protein (PBLD) was recently identified as a tumor suppressor in gastric cancer, hepatoce...

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Detalles Bibliográficos
Autores principales: Chen, Shengbo, Liu, Hongbin, Li, Zhijun, Tang, Jingyi, Huang, Bing, Zhi, Fachao, Zhao, Xinmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166876/
https://www.ncbi.nlm.nih.gov/pubmed/34059646
http://dx.doi.org/10.1038/s41419-021-03843-0