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Epithelial PBLD attenuates intestinal inflammatory response and improves intestinal barrier function by inhibiting NF-κB signaling
Intestinal barrier function defects and dysregulation of intestinal immune responses are two key contributory factors in the pathogenesis of ulcerative colitis (UC). Phenazine biosynthesis-like domain-containing protein (PBLD) was recently identified as a tumor suppressor in gastric cancer, hepatoce...
Autores principales: | Chen, Shengbo, Liu, Hongbin, Li, Zhijun, Tang, Jingyi, Huang, Bing, Zhi, Fachao, Zhao, Xinmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166876/ https://www.ncbi.nlm.nih.gov/pubmed/34059646 http://dx.doi.org/10.1038/s41419-021-03843-0 |
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