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Gender biased neuroprotective effect of Transferrin Receptor 2 deletion in multiple models of Parkinson’s disease
Alterations in the metabolism of iron and its accumulation in the substantia nigra pars compacta accompany the pathogenesis of Parkinson’s disease (PD). Changes in iron homeostasis also occur during aging, which constitutes a PD major risk factor. As such, mitigation of iron overload via chelation s...
Autores principales: | Milanese, Chiara, Gabriels, Sylvia, Barnhoorn, Sander, Cerri, Silvia, Ulusoy, Ayse, Gornati, S. V., Wallace, Daniel F., Blandini, Fabio, Di Monte, Donato A., Subramaniam, V. Nathan, Mastroberardino, Pier G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8166951/ https://www.ncbi.nlm.nih.gov/pubmed/33323945 http://dx.doi.org/10.1038/s41418-020-00698-4 |
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