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A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays

The nuclear receptor pregnane X receptor (PXR) is a ligand-dependent transcription factor that regulates genes involved in xenobiotic metabolism in mammals. Many studies suggest that PXR may play a similar role in fish. The interaction of human PXR (hPXR) with a variety of structurally diverse endog...

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Detalles Bibliográficos
Autores principales:	Creusot, Nicolas, Garoche, Clémentine, Grimaldi, Marina, Boulahtouf, Abdelhay, Chiavarina, Barbara, Bourguet, William, Balaguer, Patrick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167039/ https://www.ncbi.nlm.nih.gov/pubmed/34084152 http://dx.doi.org/10.3389/fendo.2021.665521

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