Transient incubation of cultured hippocampal neurons in the absence of magnesium induces rhythmic and synchronized epileptiform-like activity

Cell culture models are important tools to study epileptogenesis mechanisms. The aim of this work was to characterize the spontaneous and synchronized rhythmic activity developed by cultured hippocampal neurons after transient incubation in zero Mg(2+) to model Status Epilepticus. Cultured hippocamp...

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Detalles Bibliográficos
Autores principales: Mele, Miranda, Vieira, Ricardo, Correia, Bárbara, De Luca, Pasqualino, Duarte, Filipe V., Pinheiro, Paulo S., Duarte, Carlos B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167095/
https://www.ncbi.nlm.nih.gov/pubmed/34059735
http://dx.doi.org/10.1038/s41598-021-90486-y

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