Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing

Macrophages perform diverse functions within tissues during immune responses to pathogens and injury, but molecular mechanisms by which physical properties of the tissue regulate macrophage behavior are less well understood. Here, we examine the role of the mechanically activated cation channel Piez...

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Detalles Bibliográficos
Autores principales: Atcha, Hamza, Jairaman, Amit, Holt, Jesse R., Meli, Vijaykumar S., Nagalla, Raji R., Veerasubramanian, Praveen Krishna, Brumm, Kyle T., Lim, Huy E., Othy, Shivashankar, Cahalan, Michael D., Pathak, Medha M., Liu, Wendy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167181/
https://www.ncbi.nlm.nih.gov/pubmed/34059671
http://dx.doi.org/10.1038/s41467-021-23482-5

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