Cargando…

Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women

BACKGROUND: The signalling peptide endotrophin is derived through proteolytic cleavage of the carboxyl-terminal during formation of type VI collagen. It is expressed by most descendants of the mesenchymal stem cells lineage, including adipocytes and fibroblasts, and have been proposed to be a centra...

Descripción completa

Detalles Bibliográficos
Autores principales:	Staunstrup, Line Mærsk, Bager, Cecilie Liv, Frederiksen, Peder, Helge, Jørn Wulff, Brunak, Søren, Christiansen, Claus, Karsdal, Morten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167215/ https://www.ncbi.nlm.nih.gov/pubmed/34044221 http://dx.doi.org/10.1016/j.ebiom.2021.103391

Ejemplares similares

Cancer risk in relation to body fat distribution, evaluated by DXA-scans, in postmenopausal women – the Prospective Epidemiological Risk Factor (PERF) study
por: Staunstrup, Line Mærsk, et al.
Publicado: (2019)

Urinary endotrophin predicts disease progression in patients with chronic kidney disease
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2017)

Endotrophin Levels Are Associated with Allograft Outcomes in Kidney Transplant Recipients
por: Sparding, Nadja, et al.
Publicado: (2023)

Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD
por: Lindholm, Majken, et al.
Publicado: (2021)

Endotrophin, a fibroblast matrikine, may be a driver of fibroblast activation in fibro-inflammatory diseases
por: Reese-Petersen, Alexander L., et al.
Publicado: (2023)

The Mechanism for Adipose Endotrophin Production
por: Lee, Yun Sok
Publicado: (2022)

Endotrophin as a risk marker of mortality and kidney complications in a type 1 diabetes cohort
por: Møller, Alexandra Louise, et al.
Publicado: (2023)

Pretransplant endotrophin predicts delayed graft function after kidney transplantation
por: Tepel, Martin, et al.
Publicado: (2022)

Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia
por: Tang, Man-Hung Eric, et al.
Publicado: (2020)

Serum endotrophin, a type VI collagen cleavage product, is associated with increased mortality in chronic kidney disease
por: Fenton, Anthony, et al.
Publicado: (2017)

Matrix Metalloprotease Generated Fragments of Type VI Collagen Have Serum Biomarker Potential in Cancer – A Proof of Concept Study
por: Willumsen, Nicholas, et al.
Publicado: (2019)

Combination Therapy of RAS Inhibition and SGLT2 Inhibitors Decreases Levels of Endotrophin in Persons with Type 2 Diabetes
por: Møller, Alexandra Louise, et al.
Publicado: (2023)

Endotrophin is a risk marker of complications in CANagliflozin cardioVascular Assessment Study (CANVAS): a randomized controlled trial
por: Rasmussen, Daniel Guldager Kring, et al.
Publicado: (2022)

The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis
por: Holm Nielsen, S., et al.
Publicado: (2021)

Circulating levels of endotrophin and cross-linked type III collagen reflect liver fibrosis in people with HIV
por: Dold, Leona, et al.
Publicado: (2023)

Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinoma
por: Leeming, Diana Julie, et al.
Publicado: (2020)

Endotrophin – Linking Obesity with Aggressive Tumor Growth
por: Park, Jiyoung, et al.
Publicado: (2012)

The impact of endotrophin on the progression of chronic liver disease
por: Kim, Min, et al.
Publicado: (2020)

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort
por: Rønnow, Sarah R., et al.
Publicado: (2020)

Serum biomarkers reflecting specific tumor tissue remodeling processes are valuable diagnostic tools for lung cancer
por: Willumsen, Nicholas, et al.
Publicado: (2014)

Identification of heterogenous treatment response trajectories to anti-IL6 receptor treatment in rheumatoid arthritis
por: Blair, J. P. M., et al.
Publicado: (2020)

Plasma endotrophin, reflecting tissue fibrosis, is associated with graft failure and mortality in KTRs: results from two prospective cohort studies
por: Kremer, Daan, et al.
Publicado: (2022)

Endotrophin: Nominated for best supporting actor in the fibro-inflammatory saga
por: Scherer, Philipp E., et al.
Publicado: (2021)

A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis
por: Groen, Solveig Skovlund, et al.
Publicado: (2021)

Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women
por: Bertelsen, Ditte Marie, et al.
Publicado: (2018)

Endotrophin, a collagen type VI-derived matrikine, reflects the degree of renal fibrosis in patients with IgA nephropathy and in patients with ANCA-associated vasculitis
por: Sparding, Nadja, et al.
Publicado: (2021)

Blood-based extracellular matrix biomarkers as predictors of survival in patients with metastatic pancreatic ductal adenocarcinoma receiving pegvorhyaluronidase alfa
por: Wang, Song, et al.
Publicado: (2021)

‘When I can ride my bike, I think, am I at all as sick as they say?’ An exploration of how men with advanced lung cancer form illness perceptions in everyday life
por: Maersk, Jesper Larsen, et al.
Publicado: (2022)

Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design
por: Bager, Cecilie L., et al.
Publicado: (2019)

Nidogen-1 Degraded by Cathepsin S can be Quantified in Serum and is Associated with Non–Small Cell Lung Cancer
por: Willumsen, Nicholas, et al.
Publicado: (2017)

Correlation of glycemic regulation and endotrophin in patients with type 2 Diabetes; pilot study
por: Yoldemir, Sengul Aydin, et al.
Publicado: (2021)

Excessive matrix metalloprotease-mediated degradation of interstitial tissue (type I collagen) independently predicts short-term survival in an observational study of postmenopausal women diagnosed with cancer
por: Willumsen, Nicholas, et al.
Publicado: (2017)

A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype
por: Rønnow, Sarah Rank, et al.
Publicado: (2022)

Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours
por: Park, Jiyoung, et al.
Publicado: (2013)

Late-Life Risk Factors for All-Cause Dementia and Differential Dementia Diagnoses in Women: A Prospective Cohort Study
por: Neergaard, Jesper Skov, et al.
Publicado: (2016)

Total sitting time and risk of myocardial infarction, coronary heart disease and all-cause mortality in a prospective cohort of Danish adults
por: Petersen, Christina Bjørk, et al.
Publicado: (2014)

Extracellular matrix specific protein fingerprints measured in serum can separate pancreatic cancer patients from healthy controls
por: Willumsen, Nicholas, et al.
Publicado: (2013)

Determining a healthy reference range and factors potentially influencing PRO-C3 – A biomarker of liver fibrosis
por: Erhardtsen, Elisabeth, et al.
Publicado: (2021)

Endotrophin as a novel marker in PCOS and its relation with other adipokines and metabolic parameters: a pilot study
por: Guney, Gurhan, et al.
Publicado: (2021)

Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model
por: An, Yu A., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_rhn28vhs4afgfl44dhc6s7knas