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The estrogen-related receptor γ modulator, GSK5182, inhibits osteoclast differentiation and accelerates osteoclast apoptosis

Estrogen-related receptor γ (ERRγ), a member of the orphan nuclear receptor family, is a key mediator in cellular metabolic processes and energy homeostasis. Therefore, ERRγ has become an attractive target for treating diverse metabolic disorders. We recently reported that ERRγ acts as a negative re...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Ju, Yoon, Hye-Jin, Lee, Dong-Kyo, Jin, Xian, Che, Xiangguo, Choi, Je-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167243/
https://www.ncbi.nlm.nih.gov/pubmed/33612148
http://dx.doi.org/10.5483/BMBRep.2021.54.5.243