Cargando…

Increased C-Peptide Immunoreactivity in Insulin Autoimmune Syndrome (Hirata Disease) Due to High Molecular Weight Proinsulin

BACKGROUND: Determination of C-peptide is important in the investigation of unexplained hyperinsulinemic hypoglycemia because a high C-peptide concentration usually indicates endogenous insulin hypersecretion. Insulin autoimmune syndrome (IAS) denotes hyperinsulinemic hypoglycemia due to insulin-bin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kay, Richard G, Barker, Peter, Burling, Keith, Cohen, Mark, Halsall, David, Reimann, Frank, Gribble, Fiona M, Semple, Robert K, Church, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167340/ https://www.ncbi.nlm.nih.gov/pubmed/34051096 http://dx.doi.org/10.1093/clinchem/hvab043

Ejemplares similares

Assessment and Management of Anti-Insulin Autoantibodies in Varying Presentations of Insulin Autoimmune Syndrome
por: Church, David, et al.
Publicado: (2018)

Insulin Autoimmune Syndrome (Hirata Disease): A Comprehensive Review Fifty Years After Its First Description
por: Cappellani, Daniele, et al.
Publicado: (2020)

Diagnosis of insulin autoimmune syndrome using polyethylene glycol precipitation and gel filtration chromatography with ex vivo insulin exchange
por: Church, David, et al.
Publicado: (2016)

MON-135 A Case of Hirata’s Disease
por: Thumma, Soumya, et al.
Publicado: (2019)

PSUN254 Hirata's Disease - An Unexpected Surprise
por: Al-Bahadili, Huda, et al.
Publicado: (2022)

FRI665 Hirata's Syndrome: Autoimmune Hypoglycemia Diagnostic Pathway, A Mexican Case Report
por: De La Cruz, German Gonzalez, et al.
Publicado: (2023)

LC-MS/MS based detection of circulating proinsulin derived peptides in patients with altered pancreatic beta cell function
por: Foreman, Rachel E, et al.
Publicado: (2022)

Associations of age with serum insulin, proinsulin and the proinsulin-to-insulin ratio: a cross-sectional study
por: Bryhni, Bente, et al.
Publicado: (2010)

Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin
por: Durinovic-Belló, I, et al.
Publicado: (2010)

Expected values for gastrointestinal and pancreatic hormone concentrations in healthy volunteers in the fasting and postprandial state
por: Meek, Claire L, et al.
Publicado: (2020)

Tolerance to Proinsulin-1 Reduces Autoimmune Diabetes in NOD Mice
por: Jhala, Gaurang, et al.
Publicado: (2021)

Proinsulin/Insulin Autoantibodies Measured With Electrochemiluminescent Assay Are the Earliest Indicator of Prediabetic Islet Autoimmunity
por: Yu, Liping, et al.
Publicado: (2013)

Serum Insulin, Proinsulin and Proinsulin/Insulin Ratio in Type 2 Diabetic Patients: As an Index of β-Cell Function or Insulin Resistance
por: Kim, Nan Hee, et al.
Publicado: (2000)

Nationwide survey of endogenous hyperinsulinemic hypoglycemia in Japan (2017–2018): Congenital hyperinsulinism, insulinoma, non‐insulinoma pancreatogenous hypoglycemia syndrome and insulin autoimmune syndrome (Hirata’s disease)
por: Yamada, Yuki, et al.
Publicado: (2019)

PSUN237 Hirata's Disease: A rare case of IAS in An African-American
por: Bagar, Darin, et al.
Publicado: (2022)

THU390 Case Report On Hirata Syndrome: A Rare Cause Of Hypoglycemia
por: Pranala, Maanasi, et al.
Publicado: (2023)

Early Intensive Insulin Use May Preserve β-Cell Function in Neonatal Diabetes Due to Mutations in the Proinsulin Gene
por: Letourneau, Lisa R., et al.
Publicado: (2017)

Heterogeneity of glucagonomas due to differential processing of proglucagon-derived peptides
por: Challis, Benjamin G, et al.
Publicado: (2015)

The correlation between proinsulin, true insulin, proinsulin: True insulin ratio, 25(OH) D3, waist circumference and risk of prediabetes in Hainan Han adults
por: Quan, Huibiao, et al.
Publicado: (2020)

Analytical and clinical challenges in a patient with concurrent type 1 diabetes, subcutaneous insulin resistance and insulin autoimmune syndrome
por: Jassam, N, et al.
Publicado: (2014)

Proinsulin C-peptide elicits disaggregation of insulin resulting in enhanced physiological insulin effects
por: Shafqat, J., et al.
Publicado: (2006)

Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells
por: Liu, Shiqun, et al.
Publicado: (2019)

Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice
por: Levisetti, Matteo G., et al.
Publicado: (2008)

Increased seroreactivity to proinsulin and homologous mycobacterial peptides in latent autoimmune diabetes in adults
por: Niegowska, Magdalena, et al.
Publicado: (2017)

Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles
Publicado: (1986)

Gastric bypass alters the dynamics and metabolic effects of insulin and proinsulin secretion
por: Johansson, H-E., et al.
Publicado: (2007)

Insulin receptor activation by proinsulin preserves synapses and vision in retinitis pigmentosa
por: Sánchez-Cruz, Alonso, et al.
Publicado: (2022)

Distinguishing Persistent Insulin Autoantibodies With Differential Risk: Nonradioactive Bivalent Proinsulin/Insulin Autoantibody Assay
por: Yu, Liping, et al.
Publicado: (2012)

Biomolecular Simulations with the Three-Dimensional Reference Interaction Site Model with the Kovalenko-Hirata Closure Molecular Solvation Theory
por: Roy, Dipankar, et al.
Publicado: (2021)

TCF7L2 Polymorphism, Weight Loss and Proinsulin∶Insulin Ratio in the Diabetes Prevention Program
por: McCaffery, Jeanne M., et al.
Publicado: (2011)

Methods for concentration of urinary immunoreactive insulin.
por: Du, B. H., et al.
Publicado: (1986)

Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell
Publicado: (1984)

Association of obesity risk SNPs in PCSK1 with insulin sensitivity and proinsulin conversion
por: Heni, Martin, et al.
Publicado: (2010)

Mesenchymal Stem Cell Differentiation into Adipocytes Is Equally Induced by Insulin and Proinsulin In Vitro
por: Pfützner, Andreas, et al.
Publicado: (2017)

Immunoreactive insulin stability in horses at risk of insulin dysregulation
por: Leschke, Dakota H., et al.
Publicado: (2019)

Proinsulin and age in general population
por: Ateia, S, et al.
Publicado: (2013)

Glucose-Raising Genetic Variants in MADD and ADCY5 Impair Conversion of Proinsulin to Insulin
por: Wagner, Robert, et al.
Publicado: (2011)

Hyperthyroxinemia and Hypercortisolemia due to Familial Dysalbuminemia
por: Moran, Carla, et al.
Publicado: (2020)

Immunoradiometric assay of human proinsulin and partially processed proinsulin with use of monoclonal antibody and streptavidin-biotin labeling.
por: Kim, J. Q., et al.
Publicado: (1989)

Prohormone convertase 1/3 deficiency causes obesity due to impaired proinsulin processing
por: Meier, Daniel T., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lpmo4gkgpt69tk8sa7712sj433