Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases

Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the ev...

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Autores principales: Zohdy, Marwa, Cazzaniga, Simone, Nievergelt, Helga, Blum, Roland, Suter, Valérie G. A., Feldmeyer, Laurence, Beltraminelli, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167714/
https://www.ncbi.nlm.nih.gov/pubmed/33915710
http://dx.doi.org/10.3390/dermatopathology8020013
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author Zohdy, Marwa
Cazzaniga, Simone
Nievergelt, Helga
Blum, Roland
Suter, Valérie G. A.
Feldmeyer, Laurence
Beltraminelli, Helmut
author_facet Zohdy, Marwa
Cazzaniga, Simone
Nievergelt, Helga
Blum, Roland
Suter, Valérie G. A.
Feldmeyer, Laurence
Beltraminelli, Helmut
author_sort Zohdy, Marwa
collection PubMed
description Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the evaluation of dysplasia is even more complex in the presence of a lichenoid inflammation. We evaluated dysplasia in 112 oral biopsies with lichenoid inflammation in order to study the inter-observer and the intra-observer variability.
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spelling pubmed-81677142021-06-02 Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases Zohdy, Marwa Cazzaniga, Simone Nievergelt, Helga Blum, Roland Suter, Valérie G. A. Feldmeyer, Laurence Beltraminelli, Helmut Dermatopathology (Basel) Article Oral lichen planus (OLP) and oral lichenoid lesions (OLL) can both present with histological dysplasia. Despite the presence of WHO-defined criteria for the evaluation of epithelial dysplasia, its assessment is frequently subjective (inter-observer variability). The lack of reproducibility in the evaluation of dysplasia is even more complex in the presence of a lichenoid inflammation. We evaluated dysplasia in 112 oral biopsies with lichenoid inflammation in order to study the inter-observer and the intra-observer variability. MDPI 2021-04-01 /pmc/articles/PMC8167714/ /pubmed/33915710 http://dx.doi.org/10.3390/dermatopathology8020013 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zohdy, Marwa
Cazzaniga, Simone
Nievergelt, Helga
Blum, Roland
Suter, Valérie G. A.
Feldmeyer, Laurence
Beltraminelli, Helmut
Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title_full Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title_fullStr Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title_full_unstemmed Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title_short Inter-Observer and Intra-Observer Variations in the Assessment of Epithelial Dysplasia in Oral Lichenoid Diseases
title_sort inter-observer and intra-observer variations in the assessment of epithelial dysplasia in oral lichenoid diseases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167714/
https://www.ncbi.nlm.nih.gov/pubmed/33915710
http://dx.doi.org/10.3390/dermatopathology8020013
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