Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids

BACKGROUND: Metagenomic next-generation sequencing (mNGS) of body fluids is an emerging approach to identify occult pathogens in undiagnosed patients. We hypothesized that metagenomic testing can be simultaneously used to detect malignant neoplasms in addition to infectious pathogens. METHODS: From...

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Detalles Bibliográficos
Autores principales: Gu, Wei, Talevich, Eric, Hsu, Elaine, Qi, Zhongxia, Urisman, Anatoly, Federman, Scot, Gopez, Allan, Arevalo, Shaun, Gottschall, Marc, Liao, Linda, Tung, Jack, Chen, Lei, Lim, Harumi, Ho, Chandler, Kasowski, Maya, Oak, Jean, Holmes, Brittany J., Yeh, Iwei, Yu, Jingwei, Wang, Linlin, Miller, Steve, DeRisi, Joseph L., Prakash, Sonam, Simko, Jeff, Chiu, Charles Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167833/
https://www.ncbi.nlm.nih.gov/pubmed/34074327
http://dx.doi.org/10.1186/s13073-021-00912-z

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