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Ewing sarcoma of the jejunum: A case report and literature review

BACKGROUND: Ewing sarcomas (ESs) are highly aggressive malignancy and are predominant in the long bones of extremities of children and young adults with a slight male predilection and rarely presents at extra skeletal locations. CASE SUMMARY: A 55-year-old woman came to our hospital after finding el...

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Autores principales: Shadhu, Kamleshsingh, Ramlagun-Mungur, Dadhija, Ping, Xiao-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167841/
https://www.ncbi.nlm.nih.gov/pubmed/34122739
http://dx.doi.org/10.4240/wjgs.v13.i5.507
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author Shadhu, Kamleshsingh
Ramlagun-Mungur, Dadhija
Ping, Xiao-Chun
author_facet Shadhu, Kamleshsingh
Ramlagun-Mungur, Dadhija
Ping, Xiao-Chun
author_sort Shadhu, Kamleshsingh
collection PubMed
description BACKGROUND: Ewing sarcomas (ESs) are highly aggressive malignancy and are predominant in the long bones of extremities of children and young adults with a slight male predilection and rarely presents at extra skeletal locations. CASE SUMMARY: A 55-year-old woman came to our hospital after finding elevated tumor biomarkers during her physical examination. Her enhanced computed tomography scan showed a jejunal mass. The patient underwent laparoscopic enterectomy. The mass was later diagnosed as ES, evidenced by fluorescence in situ hybridization whereby the GLP ES breakpoint region 1 probe was used, showing that more than 10% of the cells showed a red-green-yellow signal proving the breakpoint rearrangement of the ES breakpoint region 1 gene in chromosome 22. CONCLUSION: We describe a case of localized ES at the jejunum in China based on the literature.
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spelling pubmed-81678412021-06-11 Ewing sarcoma of the jejunum: A case report and literature review Shadhu, Kamleshsingh Ramlagun-Mungur, Dadhija Ping, Xiao-Chun World J Gastrointest Surg Case Report BACKGROUND: Ewing sarcomas (ESs) are highly aggressive malignancy and are predominant in the long bones of extremities of children and young adults with a slight male predilection and rarely presents at extra skeletal locations. CASE SUMMARY: A 55-year-old woman came to our hospital after finding elevated tumor biomarkers during her physical examination. Her enhanced computed tomography scan showed a jejunal mass. The patient underwent laparoscopic enterectomy. The mass was later diagnosed as ES, evidenced by fluorescence in situ hybridization whereby the GLP ES breakpoint region 1 probe was used, showing that more than 10% of the cells showed a red-green-yellow signal proving the breakpoint rearrangement of the ES breakpoint region 1 gene in chromosome 22. CONCLUSION: We describe a case of localized ES at the jejunum in China based on the literature. Baishideng Publishing Group Inc 2021-05-27 2021-05-27 /pmc/articles/PMC8167841/ /pubmed/34122739 http://dx.doi.org/10.4240/wjgs.v13.i5.507 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Shadhu, Kamleshsingh
Ramlagun-Mungur, Dadhija
Ping, Xiao-Chun
Ewing sarcoma of the jejunum: A case report and literature review
title Ewing sarcoma of the jejunum: A case report and literature review
title_full Ewing sarcoma of the jejunum: A case report and literature review
title_fullStr Ewing sarcoma of the jejunum: A case report and literature review
title_full_unstemmed Ewing sarcoma of the jejunum: A case report and literature review
title_short Ewing sarcoma of the jejunum: A case report and literature review
title_sort ewing sarcoma of the jejunum: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167841/
https://www.ncbi.nlm.nih.gov/pubmed/34122739
http://dx.doi.org/10.4240/wjgs.v13.i5.507
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