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A Hill type equation can predict target gene expression driven by p53 pulsing
Many factors determine target gene expression dynamics under p53 pulsing. In this study, I sought to determine the mechanism by which duration, frequency, binding affinity and maximal transcription rate affect the expression dynamics of target genes. Using an analytical method to solve a simple mode...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167869/ https://www.ncbi.nlm.nih.gov/pubmed/33955710 http://dx.doi.org/10.1002/2211-5463.13179 |