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A Hill type equation can predict target gene expression driven by p53 pulsing

Many factors determine target gene expression dynamics under p53 pulsing. In this study, I sought to determine the mechanism by which duration, frequency, binding affinity and maximal transcription rate affect the expression dynamics of target genes. Using an analytical method to solve a simple mode...

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Detalles Bibliográficos
Autor principal: Shi, Xiaomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8167869/
https://www.ncbi.nlm.nih.gov/pubmed/33955710
http://dx.doi.org/10.1002/2211-5463.13179

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